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Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers
Strategic delivery of IRDye 700DX (photosensitizer) is a key for improving its effect in photodynamic therapy. In this study, we have synthesized IRDye 700DX-conjugated polymers containing multiple cyclic RGD peptides to deliver IRDye 700DX selectively to tumor cells and tumor-associated blood vesse...
Autores principales: | Dou, Xuebo, Nomoto, Takahiro, Takemoto, Hiroyasu, Matsui, Makoto, Tomoda, Keishiro, Nishiyama, Nobuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970177/ https://www.ncbi.nlm.nih.gov/pubmed/29802410 http://dx.doi.org/10.1038/s41598-018-26593-0 |
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