Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation

Transient activation of Src oncoprotein in non-transformed, breast epithelial cells can initiate an epigenetic switch to the stably transformed state via a positive feedback loop that involves the inflammatory transcription factors STAT3 and NF-κB. Here, we develop an experimental and computational...

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Detalles Bibliográficos
Autores principales: Ji, Zhe, He, Lizhi, Rotem, Asaf, Janzer, Andreas, Cheng, Christine S., Regev, Aviv, Struhl, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970197/
https://www.ncbi.nlm.nih.gov/pubmed/29802342
http://dx.doi.org/10.1038/s41467-018-04406-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970197/
https://www.ncbi.nlm.nih.gov/pubmed/29802342
http://dx.doi.org/10.1038/s41467-018-04406-2

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