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Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation
Transient activation of Src oncoprotein in non-transformed, breast epithelial cells can initiate an epigenetic switch to the stably transformed state via a positive feedback loop that involves the inflammatory transcription factors STAT3 and NF-κB. Here, we develop an experimental and computational...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970197/ https://www.ncbi.nlm.nih.gov/pubmed/29802342 http://dx.doi.org/10.1038/s41467-018-04406-2 |