Cargando…

Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts

G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors and are implicated in the physiological regulation of many biological processes. The high diversity of GPCRs and their physiological functions make them primary targets for therapeutic drugs. For the generation of no...

Descripción completa

Detalles Bibliográficos
Autores principales: Galinski, Sabrina, Wichert, Sven P., Rossner, Moritz J., Wehr, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970223/
https://www.ncbi.nlm.nih.gov/pubmed/29802268
http://dx.doi.org/10.1038/s41598-018-26401-9