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Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors and are implicated in the physiological regulation of many biological processes. The high diversity of GPCRs and their physiological functions make them primary targets for therapeutic drugs. For the generation of no...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970223/ https://www.ncbi.nlm.nih.gov/pubmed/29802268 http://dx.doi.org/10.1038/s41598-018-26401-9 |