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Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-RAC1 integrin and MEK-ERK pathways

As a calcium-dependent phospholipid binding annexin protein, annexin A5 (Anxa5) links to the progression, metastasis, survival, and prognosis of a variety of cancers. Current work showed ANXA5 overexpression was positively correlated with the upregulations of CRKI/II and RAC1 in hepatocarcinoma (HCC...

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Detalles Bibliográficos
Autores principales: Sun, Xujuan, Liu, Shuqing, Wang, Jinxia, Wei, Bin, Guo, Chunmei, Chen, Chen, Sun, Ming-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970249/
https://www.ncbi.nlm.nih.gov/pubmed/29802377
http://dx.doi.org/10.1038/s41419-018-0685-8