Cargando…

IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts

BACKGROUND: Metastatic breast cancer carries a poor prognosis despite the success of newly targeted therapies. Treatment options remain especially limited for the subtype of triple negative breast cancer (TNBC). Several signaling pathways, including NF-κB, are altered in TNBC, and the complexity of...

Descripción completa

Detalles Bibliográficos
Autores principales: House, Carrie D., Grajales, Valentina, Ozaki, Michelle, Jordan, Elizabeth, Wubneh, Helmae, Kimble, Danielle C., James, Jana M., Kim, Marianne K., Annunziata, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970439/
https://www.ncbi.nlm.nih.gov/pubmed/29801480
http://dx.doi.org/10.1186/s12885-018-4507-2