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Serum amyloid A primes microglia for ATP-dependent interleukin-1β release

BACKGROUND: Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA). Interleukin-1β (IL-1β), a master regulator of neuroinflammation produced by activated inflammatory cells of the myeloid line...

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Detalles Bibliográficos
Autores principales: Facci, Laura, Barbierato, Massimo, Zusso, Morena, Skaper, Stephen D., Giusti, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970445/
https://www.ncbi.nlm.nih.gov/pubmed/29803222
http://dx.doi.org/10.1186/s12974-018-1205-6