Cargando…

Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion

BACKGROUND: Parkinson’s disease (PD) is characterized by dopaminergic cell loss and inflammation in the substantia nigra (SN) leading to motor deficits but also to hippocampus-associated non-motor symptoms such as spatial learning and memory deficits. The cognitive decline is correlated with impaire...

Descripción completa

Detalles Bibliográficos
Autores principales: Hain, Elisabeth G., Sparenberg, Maria, Rasińska, Justyna, Klein, Charlotte, Akyüz, Levent, Steiner, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970532/
https://www.ncbi.nlm.nih.gov/pubmed/29803225
http://dx.doi.org/10.1186/s12974-018-1179-4