A PAX5-OCT4-PRDM1 Developmental Switch Specifies Human Primordial Germ Cells

Dysregulation of genetic pathways during human germ cell development leads to infertility. Here, we analyzed bona fide human primordial germ cells (hPGCs) to probe the developmental genetics of human germ cell specification and differentiation. We examined distribution of OCT4 occupancy in hPGCs rel...

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Detalles Bibliográficos
Autores principales: Fang, Fang, Angulo, Benjamin, Xia, Ninuo, Sukhwani, Meena, Wang, Zhengyuan, Carey, Charles C, Mazurie, Aurélien, Cui, Jun, Wilkinson, Royce, Wiedenheft, Blake, Irie, Naoko, Surani, M. Azim, Orwig, Kyle E, Pera, Renee A Reijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970969/
https://www.ncbi.nlm.nih.gov/pubmed/29713018
http://dx.doi.org/10.1038/s41556-018-0094-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970969/
https://www.ncbi.nlm.nih.gov/pubmed/29713018
http://dx.doi.org/10.1038/s41556-018-0094-3

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