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PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress

Cell and organelle membranes consist of a complex mixture of phospholipids (PLs) that determine their size, shape, and function. Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotic membranes, yet how cells sense and regulate its levels in vivo remains unclear. Here we show that...

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Detalles Bibliográficos
Autores principales: Haider, Afreen, Wei, Yu-Chen, Lim, Koini, Barbosa, Antonio D., Liu, Che-Hsiung, Weber, Ursula, Mlodzik, Marek, Oras, Kadri, Collier, Simon, Hussain, M. Mahmood, Dong, Liang, Patel, Satish, Alvarez-Guaita, Anna, Saudek, Vladimir, Jenkins, Benjamin J., Koulman, Albert, Dymond, Marcus K., Hardie, Roger C., Siniossoglou, Symeon, Savage, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971203/
https://www.ncbi.nlm.nih.gov/pubmed/29754800
http://dx.doi.org/10.1016/j.devcel.2018.04.012