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Susceptibility to corticosteroid-induced adrenal suppression: a genome-wide association study

BACKGROUND: A serious adverse effect of corticosteroid therapy is adrenal suppression. Our aim was to identify genetic variants affecting susceptibility to corticosteroid-induced adrenal suppression. METHODS: We enrolled children with asthma who used inhaled corticosteroids as part of their treatmen...

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Detalles Bibliográficos
Autores principales: Hawcutt, Daniel B, Francis, Ben, Carr, Daniel F, Jorgensen, Andrea L, Yin, Peng, Wallin, Naomi, O'Hara, Natalie, Zhang, Eunice J, Bloch, Katarzyna M, Ganguli, Amitava, Thompson, Ben, McEvoy, Laurence, Peak, Matthew, Crawford, Andrew A, Walker, Brian R, Blair, Joanne C, Couriel, Jonathan, Smyth, Rosalind L, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971210/
https://www.ncbi.nlm.nih.gov/pubmed/29551627
http://dx.doi.org/10.1016/S2213-2600(18)30058-4