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Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

Estrogen receptor α (ERα) is a successful target for ER-positive breast cancer and also reported to be relevant in many other diseases. Selective estrogen receptor modulators (SERMs) make a good therapeutic effect in clinic. Because of the drug resistance and side effects of current SERMs, the disco...

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Detalles Bibliográficos
Autores principales: Pang, Xiaocong, Fu, Weiqi, Wang, Jinhua, Kang, De, Xu, Lvjie, Zhao, Ying, Liu, Ai-Lin, Du, Guan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971309/
https://www.ncbi.nlm.nih.gov/pubmed/29861831
http://dx.doi.org/10.1155/2018/6040149