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Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches
Estrogen receptor α (ERα) is a successful target for ER-positive breast cancer and also reported to be relevant in many other diseases. Selective estrogen receptor modulators (SERMs) make a good therapeutic effect in clinic. Because of the drug resistance and side effects of current SERMs, the disco...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971309/ https://www.ncbi.nlm.nih.gov/pubmed/29861831 http://dx.doi.org/10.1155/2018/6040149 |