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Skeletal muscle mitochondrial oxidative phosphorylation function in idiopathic pulmonary arterial hypertension: in vivo and in vitro study

Mitochondrial dysfunction within the pulmonary vessels has been shown to contribute to the pathology of idiopathic pulmonary arterial hypertension (IPAH). We investigated the hypothesis of whether impaired exercise capacity observed in IPAH patients is in part due to primary mitochondrial oxidative...

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Detalles Bibliográficos
Autores principales: Sithamparanathan, Sasiharan, Rocha, Mariana C., Parikh, Jehill D., Rygiel, Karolina A., Falkous, Gavin, Grady, John P., Hollingsworth, Kieren G., Trenell, Michael I., Taylor, Robert W., Turnbull, Doug M., Gorman, Gráinne S., Corris, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971390/
https://www.ncbi.nlm.nih.gov/pubmed/29799315
http://dx.doi.org/10.1177/2045894018768290