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Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

BACKGROUND: Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories of active regulatory elements are in regions of open chromatin, and each category is associated with a specific subset of post-tr...

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Detalles Bibliográficos
Autores principales: Heuston, Elisabeth F., Keller, Cheryl A., Lichtenberg, Jens, Giardine, Belinda, Anderson, Stacie M., Hardison, Ross C., Bodine, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971425/
https://www.ncbi.nlm.nih.gov/pubmed/29807547
http://dx.doi.org/10.1186/s13072-018-0195-z