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Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points
BACKGROUND: Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories of active regulatory elements are in regions of open chromatin, and each category is associated with a specific subset of post-tr...
Autores principales: | Heuston, Elisabeth F., Keller, Cheryl A., Lichtenberg, Jens, Giardine, Belinda, Anderson, Stacie M., Hardison, Ross C., Bodine, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971425/ https://www.ncbi.nlm.nih.gov/pubmed/29807547 http://dx.doi.org/10.1186/s13072-018-0195-z |
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