Small molecules that inhibit the late stage of Munc13-4–dependent secretory granule exocytosis in mast cells

Ca(2+)-dependent secretory granule fusion with the plasma membrane is the final step for the exocytic release of inflammatory mediators, neuropeptides, and peptide hormones. Secretory cells use a similar protein machinery at late steps in the regulated secretory pathway, employing protein isoforms f...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruinsma, Stephen, James, Declan J., Quintana Serrano, Melanie, Esquibel, Joseph, Woo, Sang Su, Kielar-Grevstad, Elle, Crummy, Ellen, Qurashi, Rehan, Kowalchyk, Judy A., Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971468/
https://www.ncbi.nlm.nih.gov/pubmed/29615494
http://dx.doi.org/10.1074/jbc.RA117.001547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971468/
https://www.ncbi.nlm.nih.gov/pubmed/29615494
http://dx.doi.org/10.1074/jbc.RA117.001547

Ejemplares similares