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Dexmedetomidine protects against oxygen-glucose deprivation/reoxygenation injury-induced apoptosis via the p38 MAPK/ERK signalling pathway
OBJECTIVE: To investigate the protective effects of dexmedetomidine (DEX) in oxygen-glucose deprivation/reoxygenation (OGD/R) injury, which is involved in a number of ischaemic diseases. METHODS: An in vitro OGD/R injury model was generated using mouse Neuro 2A neuroblastoma (N2A) cells. Different c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971521/ https://www.ncbi.nlm.nih.gov/pubmed/29210287 http://dx.doi.org/10.1177/0300060517734460 |