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Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System

Following antiretroviral therapy, HIV-infected patients show increased circulating levels of the antidiabetic hormone fibroblast growth factor 21 (FGF21). In contrast, the expression of the FGF21-obligatory coreceptor β-Klotho (KLB) is reduced in target tissues. This situation is comparable to the F...

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Detalles Bibliográficos
Autores principales: Moure, Ricardo, Domingo, Pere, Villarroya, Joan, Gasa, Laura, Gallego-Escuredo, José M., Quesada-López, Tania, Morón-Ros, Samantha, Maroto, Alberto F., Mateo, Gracia M., Domingo, Joan C., Villarroya, Francesc, Giralt, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971578/
https://www.ncbi.nlm.nih.gov/pubmed/29661866
http://dx.doi.org/10.1128/AAC.00029-18