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Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice

Combination therapy has been proposed as an alternative therapeutic approach for the treatment of Chagas disease. In this study, we evaluated the effect of treatment with benznidazole combined with E1224 (ravuconazole prodrug) in an experimental murine model of acute infection. The first set of expe...

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Detalles Bibliográficos
Autores principales: Diniz, Lívia de Figueiredo, Mazzeti, Ana Lia, Caldas, Ivo Santana, Ribeiro, Isabela, Bahia, Maria Terezinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971593/
https://www.ncbi.nlm.nih.gov/pubmed/29555633
http://dx.doi.org/10.1128/AAC.00401-18