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Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice
Combination therapy has been proposed as an alternative therapeutic approach for the treatment of Chagas disease. In this study, we evaluated the effect of treatment with benznidazole combined with E1224 (ravuconazole prodrug) in an experimental murine model of acute infection. The first set of expe...
Autores principales: | Diniz, Lívia de Figueiredo, Mazzeti, Ana Lia, Caldas, Ivo Santana, Ribeiro, Isabela, Bahia, Maria Terezinha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971593/ https://www.ncbi.nlm.nih.gov/pubmed/29555633 http://dx.doi.org/10.1128/AAC.00401-18 |
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