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Antiproliferative effect of urolithin A, the ellagic acid-derived colonic metabolite, on hepatocellular carcinoma HepG2.2.15 cells by targeting Lin28a/let-7a axis

An abnormality in the Lin28/let-7a axis is relevant to the progression of hepatitis B virus (HBV)-positive hepatocellular carcinoma (HCC), which could be a novel therapeutic target for this malignant tumor. The present study aimed to investigate the antiproliferative and anti-invasive effects of uro...

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Detalles Bibliográficos
Autores principales: Qiu, Zhenpeng, Zhou, Junxuan, Zhang, Cong, Cheng, Ye, Hu, Junjie, Zheng, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972012/
https://www.ncbi.nlm.nih.gov/pubmed/29742265
http://dx.doi.org/10.1590/1414-431X20187220