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Hypoxia-induced hyperpermeability of rat glomerular endothelial cells involves HIF-2α mediated changes in the expression of occludin and ZO-1

This study aimed to investigate the role of hypoxia-inducible factor-2α (HIF-2α) in the expression of tight junction proteins and permeability alterations in rat glomerular endothelial cells (rGENCs) under hypoxia conditions. The expression level of HIF-2α and tight junction proteins (occludin and Z...

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Detalles Bibliográficos
Autores principales: Luo, Peng-Li, Wang, Yan-Jun, Yang, Yan-Yan, Yang, Jia-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972023/
https://www.ncbi.nlm.nih.gov/pubmed/29791586
http://dx.doi.org/10.1590/1414-431X20186201