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Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription

PEAK1 is a newly described tyrosine kinase and scaffold protein that transmits integrin-mediated extracellular matrix (ECM) signals to facilitate cell movement and growth. While aberrant expression of PEAK1 has been linked to cancer progression, its normal physiological role in vertebrate biology is...

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Detalles Bibliográficos
Autores principales: Wang, Huawei, Lapek, John, Fujimura, Ken, Strnadel, Jan, Liu, Bei, Gonzalez, David J., Zhang, Wei, Watson, Felicia, Yu, Vicky, Liu, Chao, Melo, Carina Muccilo, Miller, Yury I., Elliott, Kathryn C., Cheresh, David A., Klemke, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972149/
https://www.ncbi.nlm.nih.gov/pubmed/29872538
http://dx.doi.org/10.1038/s41421-018-0024-3