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Optimizing Column Length and Particle Size in Preparative Batch Chromatography Using Enantiomeric Separations of Omeprazole and Etiracetam as Models: Feasibility of Taguchi Empirical Optimization

The overreaching purpose of this study is to evaluate new approaches for determining the optimal operational and column conditions in chromatography laboratories, i.e., how best to select a packing material of proper particle size and how to determine the proper length of the column bed after select...

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Detalles Bibliográficos
Autores principales: Samuelsson, Jörgen, Leśko, Marek, Enmark, Martin, Högblom, Joakim, Karlsson, Anders, Kaczmarski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972160/
https://www.ncbi.nlm.nih.gov/pubmed/29887619
http://dx.doi.org/10.1007/s10337-018-3519-z