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Immobilized Osteopontin Enhances Adhesion but Suppresses Cytokine Release of Anti-IgE Activated Human Mast Cells

Osteopontin (OPN) is an Arg-Gly-Asp (RGD)-containing extracellular matrix protein which is upregulated in inflamed tissues and has been reported to modulate mast cell activities in mice. Due to the known heterogeneity among mast cells of different species and the important roles of mast cells in all...

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Detalles Bibliográficos
Autores principales: Ng, Chun Wai, Tam, Issan Yee San, Sam, Sze Wing, Yu, Yangyang, Lau, Hang Yung Alaster
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972195/
https://www.ncbi.nlm.nih.gov/pubmed/29872439
http://dx.doi.org/10.3389/fimmu.2018.01109