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Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription

Influenza virus intimately associates with host RNA polymerase II (Pol II) and mRNA processing machinery. Here, we use mammalian native elongating transcript sequencing (mNET-seq) to examine Pol II behavior during viral infection. We show that influenza virus executes a two-pronged attack on host tr...

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Detalles Bibliográficos
Autores principales: Bauer, David L.V., Tellier, Michael, Martínez-Alonso, Mónica, Nojima, Takayuki, Proudfoot, Nick J., Murphy, Shona, Fodor, Ervin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972227/
https://www.ncbi.nlm.nih.gov/pubmed/29768209
http://dx.doi.org/10.1016/j.celrep.2018.04.047