CD133 expression and MYCN amplification induce chemoresistance and reduce average survival time in pediatric neuroblastoma

OBJECTIVES: Neuroblastoma (NB) is the most common pediatric solid tumor derived from the sympathetic nervous system. MYCN is amplified in nearly half of patients with NB, and its association with rapid disease progression and poor outcome is controversial. Characterization of cancer stem cells (CSCs...

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Detalles Bibliográficos
Autores principales: Zhong, Zhi-Yong, Shi, Bao-Jun, Zhou, Hui, Wang, Wen-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Clinical Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972240/
https://www.ncbi.nlm.nih.gov/pubmed/29322842
http://dx.doi.org/10.1177/0300060517732256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972240/
https://www.ncbi.nlm.nih.gov/pubmed/29322842
http://dx.doi.org/10.1177/0300060517732256

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