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Role of the hippocampal 5-HT1A receptor-mediated cAMP/PKA signalling pathway in sevoflurane-induced cognitivedysfunction in aged rats

OBJECTIVE: This study aimed to evaluate the role of the hippocampal 5-hydroxytryptamine-1A (5-HT1A)-mediated cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) signalling pathway in sevoflurane-induced cognitive dysfunction in aged rats. METHODS: Sixty 18-month-old Sprague–Dawley rats were d...

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Detalles Bibliográficos
Autores principales: Qiu, Yi, Wang, Ying, Wang, Xiaodong, Wang, Caixia, Xia, Zhong-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972259/
https://www.ncbi.nlm.nih.gov/pubmed/29332488
http://dx.doi.org/10.1177/0300060517744037