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Perspectives on Chimeric Antigen Receptor T-Cell Immunotherapy for Solid Tumors
Chimeric antigen receptor (CAR) T-cell therapy entails the genetic engineering of a patient’s T-cells to express membrane spanning fusion receptors with defined specificities for tumor-associated antigens. These CARs are capable of eliciting robust T-cell activation to initiate killing of the target...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972325/ https://www.ncbi.nlm.nih.gov/pubmed/29872437 http://dx.doi.org/10.3389/fimmu.2018.01104 |