Perspectives on Chimeric Antigen Receptor T-Cell Immunotherapy for Solid Tumors

Chimeric antigen receptor (CAR) T-cell therapy entails the genetic engineering of a patient’s T-cells to express membrane spanning fusion receptors with defined specificities for tumor-associated antigens. These CARs are capable of eliciting robust T-cell activation to initiate killing of the target...

Descripción completa

Detalles Bibliográficos
Autores principales: Kosti, Paris, Maher, John, Arnold, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972325/
https://www.ncbi.nlm.nih.gov/pubmed/29872437
http://dx.doi.org/10.3389/fimmu.2018.01104

Ejemplares similares

Ejemplares similares