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Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD
BACKGROUND: Extracellular adenosine triphosphate (ATP) is up-regulated in the airways of patients with chronic obstructive pulmonary disease (COPD), resulting in increased inflammation, bronchoconstriction, and cough. Although extracellular ATP levels are tightly controlled by nucleoside triphosphat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972409/ https://www.ncbi.nlm.nih.gov/pubmed/29807526 http://dx.doi.org/10.1186/s12931-018-0793-0 |