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Molecular Characterization of Iranian Patients with Inherited Coagulation Factor VII Deficiency

Coagulation factor VII (FVII) is a key enzyme of the extrinsic coagulation cascade that is predominantly produced by hepatocytes. The F7 gene mutations cause FVII deficiency with considerable molecular and phenotypic heterogeneity. We characterized the molecular alterations of the F7 gene and their...

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Detalles Bibliográficos
Autores principales: Shahbazi, S, Mahdian, R, Karimi, K, Mashayekhi, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972499/
https://www.ncbi.nlm.nih.gov/pubmed/29876229
http://dx.doi.org/10.1515/bjmg-2017-0027