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A rapid epistatic mixed-model association analysis by linear retransformations of genomic estimated values

MOTIVATION: Epistasis provides a feasible way for probing potential genetic mechanism of complex traits. However, time-consuming computation challenges successful detection of interaction in practice, especially when linear mixed model (LMM) is used to control type I error in the presence of populat...

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Detalles Bibliográficos
Autores principales: Ning, Chao, Wang, Dan, Kang, Huimin, Mrode, Raphael, Zhou, Lei, Xu, Shizhong, Liu, Jian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972602/
https://www.ncbi.nlm.nih.gov/pubmed/29342229
http://dx.doi.org/10.1093/bioinformatics/bty017