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A rapid epistatic mixed-model association analysis by linear retransformations of genomic estimated values
MOTIVATION: Epistasis provides a feasible way for probing potential genetic mechanism of complex traits. However, time-consuming computation challenges successful detection of interaction in practice, especially when linear mixed model (LMM) is used to control type I error in the presence of populat...
Autores principales: | Ning, Chao, Wang, Dan, Kang, Huimin, Mrode, Raphael, Zhou, Lei, Xu, Shizhong, Liu, Jian-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972602/ https://www.ncbi.nlm.nih.gov/pubmed/29342229 http://dx.doi.org/10.1093/bioinformatics/bty017 |
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