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Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways
Understanding the functional properties of cells of different origins is a long-standing challenge of personalized medicine. Especially in cancer, the high heterogeneity observed in patients slows down the development of effective cures. The molecular differences between cell types or between health...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972629/ https://www.ncbi.nlm.nih.gov/pubmed/29872402 http://dx.doi.org/10.3389/fphys.2018.00550 |