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Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways
Understanding the functional properties of cells of different origins is a long-standing challenge of personalized medicine. Especially in cancer, the high heterogeneity observed in patients slows down the development of effective cures. The molecular differences between cell types or between health...
Autores principales: | De Landtsheer, Sébastien, Lucarelli, Philippe, Sauter, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972629/ https://www.ncbi.nlm.nih.gov/pubmed/29872402 http://dx.doi.org/10.3389/fphys.2018.00550 |
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