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The human cytomegalovirus terminase complex as an antiviral target: a close-up view

Human cytomegalovirus (HCMV) is responsible for life-threatening infections in immunocompromised individuals and can cause serious congenital malformations. Available antivirals target the viral polymerase but are subject to cross-resistance and toxicity. New antivirals targeting other replication s...

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Detalles Bibliográficos
Autores principales: Ligat, G, Cazal, R, Hantz, S, Alain, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972660/
https://www.ncbi.nlm.nih.gov/pubmed/29361041
http://dx.doi.org/10.1093/femsre/fuy004