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Non-Decaying postsynaptics potentials and delayed spikes in hippocampal pyramidal neurons generated by a zero slope conductance created by the persistent Na(+) current

The negative slope conductance created by the persistent sodium current (I(NaP)) prolongs the decay phase of excitatory postsynaptic potentials (EPSPs). In a recent study, we demonstrated that this effect was due to an increase of the membrane time constant. When the negative slope conductance oppos...

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Detalles Bibliográficos
Autores principales: Ceballos, Cesar C., Pena, Rodrigo F. O., Roque, Antônio C., Leão, Ricardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972798/
https://www.ncbi.nlm.nih.gov/pubmed/29380651
http://dx.doi.org/10.1080/19336950.2018.1433940