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Mechanistic insight into the suppression of microglial ROS production by voltage-gated proton channels (VSOP/Hv1)

Voltage-gated proton channels (VSOP/Hv1) reportedly promote reactive oxygen species (ROS) production in several immune cell types. However, we recently reported that primary microglia from VSOP/Hv1-deficient mice show higher ROS production than those from WT mice. Microglia may show a distinct activ...

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Detalles Bibliográficos
Autores principales: Kawai, Takafumi, Tatsumi, Shoki, Kihara, Shinji, Sakimura, Kenji, Okamura, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972804/
https://www.ncbi.nlm.nih.gov/pubmed/28961043
http://dx.doi.org/10.1080/19336950.2017.1385684