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Pharmacologic targeting of endothelial Ca(2+)-activated K(+) channels: A strategy to improve cardiovascular function

Endothelial small and intermediate-conductance, Ca(2+)-activated K(+) channels (KCa2.3 and KCa3.1, respectively) play an important role in the regulation of vascular function and systemic blood pressure. Growing evidence indicates that they are intimately involved in agonist-evoked vasodilation of s...

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Detalles Bibliográficos
Autores principales: Mathew John, Cini, Khaddaj Mallat, Rayan, George, Grace, Kim, Taeyeob, Mishra, Ramesh C., Braun, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972810/
https://www.ncbi.nlm.nih.gov/pubmed/29577810
http://dx.doi.org/10.1080/19336950.2018.1454814