Cargando…

Pharmacologic targeting of endothelial Ca(2+)-activated K(+) channels: A strategy to improve cardiovascular function

Endothelial small and intermediate-conductance, Ca(2+)-activated K(+) channels (KCa2.3 and KCa3.1, respectively) play an important role in the regulation of vascular function and systemic blood pressure. Growing evidence indicates that they are intimately involved in agonist-evoked vasodilation of s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathew John, Cini, Khaddaj Mallat, Rayan, George, Grace, Kim, Taeyeob, Mishra, Ramesh C., Braun, Andrew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972810/ https://www.ncbi.nlm.nih.gov/pubmed/29577810 http://dx.doi.org/10.1080/19336950.2018.1454814

Ejemplares similares

Pharmacological Targeting of KCa Channels to Improve Endothelial Function in the Spontaneously Hypertensive Rat
por: Khaddaj Mallat, Rayan, et al.
Publicado: (2019)

MAG‐DPA curbs inflammatory biomarkers and pharmacological reactivity in cytokine‐triggered hyperresponsive airway models
por: Khaddaj‐Mallat, Rayan, et al.
Publicado: (2016)

Effects of Pharmacological Inhibitors of NADPH Oxidase on Myogenic Contractility and Evoked Vasoactive Responses in Rat Resistance Arteries
por: Kendrick, Dylan J., et al.
Publicado: (2022)

Pro-Resolving Effects of Resolvin D(2) in LTD(4) and TNF-α Pre-Treated Human Bronchi
por: Khaddaj-Mallat, Rayan, et al.
Publicado: (2016)

Endothelial Cell Focal Adhesion Regulates Transendothelial Migration and Subendothelial Crawling of T Cells
por: Lee, Jaehyun, et al.
Publicado: (2018)

Pharmacological Evidence Suggests That Slo3 Channel Is the Principal K(+) Channel in Boar Spermatozoa
por: Cooray, Akila, et al.
Publicado: (2023)

SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein
por: Khaddaj-Mallat, Rayan, et al.
Publicado: (2021)

Ca(2+)-activated K(+) Channels in Murine Endothelial Cells: Block by Intracellular Calcium and Magnesium
por: Ledoux, Jonathan, et al.
Publicado: (2008)

Small-conductance Ca(2+)-activated K(+) channels: insights into their roles in cardiovascular disease
por: Gu, Mingxia, et al.
Publicado: (2018)

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of K(Ca)2.x and K(Ca)3.1 Channels
por: Kloza, Monika, et al.
Publicado: (2019)

K(Ca)2 and K(Ca)3 Channels in Learning and Memory Processes, and Neurodegeneration
por: Kuiper, Els F. E., et al.
Publicado: (2012)

A Compact UWB Antenna with Independently Controllable Notch Bands
por: Iqbal, Amjad, et al.
Publicado: (2019)

CaMKII regulation of cardiac K channels
por: Mustroph, Julian, et al.
Publicado: (2014)

Manzuaat wa Musharadat, Uprooted and Scattered: Refugee Women Escape Journey and the Longing to Return to Syria
por: Rizkalla, Niveen, et al.
Publicado: (2021)

Cancer-Associated Intermediate Conductance Ca(2+)-Activated K(+) Channel K(Ca)3.1
por: Mohr, Corinna J., et al.
Publicado: (2019)

K(Ca)2 and K(Ca)3.1 Channels in the Airways: A New Therapeutic Target
por: Orfali, Razan, et al.
Publicado: (2023)

Pharmacological Strategies for Manipulating Plant Ca(2+) Signalling
por: De Vriese, Kjell, et al.
Publicado: (2018)

Structure, gating, and pharmacology of human Ca(V)3.3 channel
por: He, Lingli, et al.
Publicado: (2022)

Pharmacological and kinetic analysis of K channel gating currents
Publicado: (1989)

Functional Interaction among K(Ca) and TRP Channels for Cardiovascular Physiology: Modern Perspectives on Aging and Chronic Disease
por: Behringer, Erik J., et al.
Publicado: (2019)

K(+)-Dependent Selectivity and External Ca(2+) Block of Shab K(+) Channels
por: Carrillo, Elisa, et al.
Publicado: (2015)

K(+) and Ca(2+) Channels Regulate Ca(2+) Signaling in Chondrocytes: An Illustrated Review
por: Suzuki, Yoshiaki, et al.
Publicado: (2020)

Membrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca(2+)-activated K Channel
por: Thompson, Jill, et al.
Publicado: (2006)

Pharmacological Inhibition of Voltage-gated Ca(2+) Channels for Chronic Pain Relief
por: Lee, Seungkyu
Publicado: (2013)

Glucose and Pharmacological Modulators of ATP-Sensitive K(+) Channels Control [Ca(2+)](c) by Different Mechanisms in Isolated Mouse α-Cells
por: Quoix, Nicolas, et al.
Publicado: (2009)

Cylindrical Dielectric Resonator Antenna-Based Sensors for Liquid Chemical Detection
por: Iqbal, Amjad, et al.
Publicado: (2019)

Ca(2+)-activated K+ channels in human leukemic T cells
Publicado: (1992)

K(Ca)3.1 Channels and Glioblastoma: In Vitro Studies
por: Klumpp, Lukas, et al.
Publicado: (2018)

Pro-inflammatory Ca(++)-activated K(+) channels are inhibited by hydroxychloroquine
por: Eugenia Schroeder, María, et al.
Publicado: (2017)

Role of K(+) and Ca(2+)-Permeable Channels in Osteoblast Functions
por: Kito, Hiroaki, et al.
Publicado: (2021)

Ca(2+)-Activated K(+) Channels and the Regulation of the Uteroplacental Circulation
por: Hu, Xiang-Qun, et al.
Publicado: (2023)

Effective gating charges per channel in voltage-dependent K+ and Ca2+ channels
Publicado: (1996)

Pharmacology and Surface Electrostatics of the K Channel Outer Pore Vestibule
por: Quinn, Claire C., et al.
Publicado: (2007)

Functional Regulation of K(ATP) Channels and Mutant Insight Into Clinical Therapeutic Strategies in Cardiovascular Diseases
por: Wang, Zhicheng, et al.
Publicado: (2022)

Functional K(Ca)3.1 K(+) channels are required for human fibrocyte migration
por: Cruse, Glenn, et al.
Publicado: (2011)

Controlling Ca(2+)-Activated K(+) Channels with Models of Ca(2+) Buffering in Purkinje Cells
por: Anwar, Haroon, et al.
Publicado: (2010)

Cardiovascular K(ATP) channels and advanced aging
por: Yang, Hua-Qian, et al.
Publicado: (2016)

Internalization and Transportation of Endothelial Cell Surface K(Ca)2.3 and K(Ca)3.1 in Normal Pregnancy and Preeclampsia
por: Choi, Shinkyu, et al.
Publicado: (2019)

Inhibition of K(Ca)2.2 and K(Ca)2.3 channel currents by protonation of outer pore histidine residues
por: Goodchild, Samuel J., et al.
Publicado: (2009)

Stabilizing ER Ca(2+) Channel Function as an Early Preventative Strategy for Alzheimer’s Disease
por: Chakroborty, Shreaya, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_vt7jhlv5jueih8h6b4osdege81