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Sensing and regulation of cell volume – we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?

Cellular volume changes lead to initiation of cell volume regulatory events, the molecular identity of which remains unresolved. We here discuss experimental challenges associated with investigation of volume regulation during application of large, non-physiological osmotic gradients. The TRPV4 ion...

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Detalles Bibliográficos
Autores principales: Toft-Bertelsen, Trine L., Larsen, Brian R., MacAulay, Nanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972811/
https://www.ncbi.nlm.nih.gov/pubmed/29424275
http://dx.doi.org/10.1080/19336950.2018.1438009