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自噬在EGFR-TKI类肿瘤靶向药物对肺癌的治疗和耐药中作用的研究进展

Epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) is a group of targeted-drugs which effectively inhibits the growth of tumor cells with sensitive mutations in EGFR. However, the innate and acquired resistance are major obstacles of the efficiency. Autophagy is a highly conserved...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972950/
https://www.ncbi.nlm.nih.gov/pubmed/27666552
http://dx.doi.org/10.3779/j.issn.1009-3419.2016.09.09