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H2228细胞和EML4-ALK阳性肺癌组织中SOCS3基因启动子区甲基化状态的研究

BACKGROUND AND OBJECTIVE: The EML4-ALK fusion gene is a newly discovered driver gene of non-small cell lung cancer and exhibits special clinical and pathological features. The JAK-STAT signaling pathway, an important downstream signaling pathway of EML4-ALK, is aberrantly sustained and activated in...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972959/
https://www.ncbi.nlm.nih.gov/pubmed/27666544
http://dx.doi.org/10.3779/j.issn.1009-3419.2016.09.01