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Discovering a binary CTCF code with a little help from BORIS

CCCTC-binding factor (CTCF) is a conserved, essential regulator of chromatin architecture containing a unique array of 11 zinc fingers (ZFs). Gene duplication and sequence divergence during early amniote evolution generated the CTCF paralog Brother Of the Regulator of Imprinted Sites (BORIS), which...

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Detalles Bibliográficos
Autores principales: Lobanenkov, Victor V., Zentner, Gabriel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973138/
https://www.ncbi.nlm.nih.gov/pubmed/29077515
http://dx.doi.org/10.1080/19491034.2017.1394536