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Extrusion without a motor: a new take on the loop extrusion model of genome organization

Chromatin loop extrusion is a popular model for the formation of CTCF loops and topological domains. Recent HiC data have revealed a strong bias in favour of a particular arrangement of the CTCF binding motifs that stabilize loops, and extrusion is the only model to date which can explain this. Howe...

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Detalles Bibliográficos
Autores principales: Brackley, C. A., Johnson, J., Michieletto, D., Morozov, A. N., Nicodemi, M., Cook, P. R., Marenduzzo, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973195/
https://www.ncbi.nlm.nih.gov/pubmed/29300120
http://dx.doi.org/10.1080/19491034.2017.1421825