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Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma

PURPOSE: Osteosarcoma (OS) is the most common type of primary solid bone tumor. Ovo-like zinc finger 2 (Ovol2), a zinc finger transcription factor, is a mesenchymal–epithelial transition (MET) driver that induces miR-200 expression in prostate cancer, breast cancer, and hepatocellular carcinoma. How...

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Detalles Bibliográficos
Autores principales: Liu, Jijun, Wu, Qi, Wang, Yonggui, Wei, Yulong, Wu, Hong, Duan, Lijun, Zhang, Qiang, Wu, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973319/
https://www.ncbi.nlm.nih.gov/pubmed/29872308
http://dx.doi.org/10.2147/OTT.S157119