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The methylation profiles of PRDM promoters in non–small cell lung cancer

BACKGROUND: Non–small cell lung cancer (NSCLC) is one of the leading malignant tumors worldwide. Aberrant gene promoter methylation contributes to NSCLC, and PRDM is a tumor suppressor gene family that possesses histone methyltransferase activity. This study aimed to investigate whether aberrant met...

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Detalles Bibliográficos
Autores principales: Tan, Shuang-xiang, Hu, Rui-cheng, Xia, Qian, Tan, Yong-li, Liu, Jing-jing, Gan, Gui-xiang, Wang, Li-le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973400/
https://www.ncbi.nlm.nih.gov/pubmed/29872311
http://dx.doi.org/10.2147/OTT.S156775