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Association between leptin gene rs7799039 polymorphism and lipid profile changes induced by isotretinoin treatment in acne patients

INTRODUCTION: Isotretinoin, a vitamin A-derived medication, is one of the effective treatments for severe acne. However, in a fraction of patients, this treatment causes significant adverse effects. Leptin is a pro-inflammatory cytokine that plays a role in apoptosis of adipose cells and sebaceous l...

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Detalles Bibliográficos
Autores principales: Khabour, Omar F, Alzoubi, Karem H, Firoz, Abdul Samad, Al-Awad, Rafat MM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973407/
https://www.ncbi.nlm.nih.gov/pubmed/29872305
http://dx.doi.org/10.2147/TCRM.S165712